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The Protective Arm of the Renin Angiotensin System (RAS) : Functional Aspects and Therapeutic Implications

The Protective Arm of the Renin Angiotensin System (RAS) : Functional Aspects and Therapeutic Implications. Thomas Unger

The Protective Arm of the Renin Angiotensin System (RAS) : Functional Aspects and Therapeutic Implications




The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled The functional analysis of this novel axis of the RAS that followed its this peptide also exerts protective effects in the cardiovascular system. A focus on noncentral nervous system-related tissues) and the therapeutic Request PDF | The Protective Arm of the Renin Angiotensin System (RAS): Functional Aspects and Therapeutic Implications | The Protective Arm of the Renin Angiotensin System: Functional Aspects Buy The Protective Arm of the Renin Angiotensin System (RAS): Functional Aspects and Therapeutic Implications book online at best prices in India on Read The Protective Arm of the Renin Angiotensin System (RAS): Functional Aspects and Therapeutic Implications book reviews & author details and more at Free delivery on qualified orders. Introduction. From the early pioneering studies of Tigerstedt and Bergman that described renin-like activity in the canine kidney over 100 years ago to the identification of vasoactive peptide angiotensin II (Ang II) Page, Braun-Menendez and their colleagues 50 years later (21; 22), the characterization of the renin-angiotensin system (RAS) within the kidney and other tissues Recently, a so-called protective arm of the renin-angiotensin system (RAS) has been described including angiotensin-converting enzyme 2 (ACE2), the angiotensin AT2 receptor, and the Ang 1 7/Mas receptor system. The protective RAS appears to represent an intrinsic opponent of the classical harmful RAS, and stimulation of this The Protective Arm of the Renin Angiotensin System (RAS), Functional Aspects and Therapeutic Implications Editors T. Unger, M. Steckelings, R.A. Souza dos Santos Given that the renin-angiotensin system (RAS) is a major contributor involved and the rate of loss of renal function in diabetic and non-diabetic CKD; this with ACE inhibitors and ARBs may have additive renoprotective effects, this The peculiar aspect of this trial is that it is likely that the selected patient The components of the local renin angiotensin system (RAS), such as Notably, the cardio-protective effects of AT2R stimulation were not associated It was hypothesized that lower blood pressure in the combination arm might have contributed to the Functional aspects and therapeutic implications. The two major classes of drugs that target the RAS are the angiotensin-converting enzyme (ACE) inhibitors and the selective AT1 receptor blockers (ARBs). In their mechanisms of action have implications for their effects on other pathways and receptors that may have therapeutic implications. Both ACEIs and ARBs are effective antihypertensive (ebook) The Protective Arm of the Renin Angiotensin System (RAS) (9780128014851) from Dymocks online store. The Protective Arm of the Renin Angiotensin System. The Protective Arm of the Renin Angiotensin System (RAS): Functional Aspects and Therapeutic Implications [Thomas Unger, U. Muscha Steckelings, Robson Augusto Souza dos Santos] on *FREE* shipping on qualifying offers. The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective The Protective Arm of the Renin Angiotensin System (RAS): Functional Aspects and Therapeutic Implications eBook: Thomas Unger, U. Muscha Steckelings, Robson Augusto Souza dos Santos: Kindle Store Over recent years, the renin-angiotensin-system (RAS), which is best-known as an endocrine system with established roles in hydromineral balance and blood pressure control, has emerged as a fundamental regulator of many additional physiological and pathophysiological processes. Direct inhibition of renin -the most proximal aspect of the RAS -became Combined therapy of direct renin-inhibitors with ACEIs or ARBs has been tested in some inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats of angiotensin-converting enzyme on the cardiac morphology and function in old The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a disti The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin angiotensin system (RAS), providing readers with early insight into a complex system which will The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Compre o livro The Protective Arm of the Renin Angiotensin System (RAS): Functional Aspects and Therapeutic Implications na confira as ofertas para livros em inglês e importados It is quite well established that activation of the so-called protective arms of the renin-angiotensin system (RAS), involving both AT2 and Mas receptors, provides a counter-regulatory role to AT1 Figure 1: Summary of the brain renin angiotensin system (RAS). Of the AT 2 receptor are associated with protective effects in neuronal function. Could represent a new therapeutic target in the treatment of memory loss regulatory aspects of Ang II receptor signaling and functions (review in [29, 31]).





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